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NEUROMODULATION DEVICES
The neuroscience technologies listed below provide open access to collaborate with neuromodulation device innovators and/or product specialists with the goal of the researcher achieving their research modalities apart from us, ensuring that the researcher maximizes the utilization of the device.
• Brainwave Bulletin •
Electric field temporal interference stimulation of neurons in vitro
Sara Tremblay, Vincent Beaulé, Sébastien Proulx, Louis-Philippe Lafleur, Julien Doyon, Małgorzata Marjańska and Hugo Théoret
tES
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Neural Hub
In a 48-patient randomized double-blind placebo-controlled study, Sinaptica’s personalized rTMS-EEG neuromodulation was shown to significantly preserve cognition and function and reduced behavioral disturbances after 12 months, compared to placebo. These results build on positive results from an earlier 6-month study published in the peer-reviewed Oxford University Press journal, Brain.
Noninvasive Neuromodulation:
A True Breakthrough in Alzheimer's Disease
A Bold New Approach with Unprecedented Clinical Trial Results
Sinaptica’s scientific co-founders have published positive Phase 2 placebo-controlled results that show our closed-loop neuromodulation therapy shows statistically significant slowing of Alzheimer’s disease progression at 12 months, as measured by four different gold-standard cognitive & functional clinical trial endpoints.
CAMBRIDGE, Mass. (BUSINESS WIRE) Sinaptica Therapeutics, Inc., a clinical-stage company leading the development of a new class of personalized neuromodulation therapeutics to treat Alzheimer’s and other primary neurodegenerative diseases, today announced that co-development of the SinaptiStim® Neuromodulation System is underway, with planned March delivery of the first clinical system for validation testing and use in forthcoming clinical trials. Partner Nexstim (NXTMH:HEX) is customizing the system to Sinaptica’s specifications, incorporating high resolution 64-channel electroencephalography (EEG) from industry leader Bittium (BITTI:HEX) to enable precision calibration of the therapy for each Alzheimer’s patient. The new system will be used in Sinaptica’s upcoming clinical trials in Alzheimer’s patients and beyond, with multiple trials scheduled to begin in 2025.
Scientific Discussion: Neuromodulation Devices Integration for Translational Applications
Neuromodulation is the strategic alteration of neural activity through the delivery of targeted stimuli—electrical, chemical, or magnetic—to achieve desired physiological outcomes. Integration of neuromodulation devices into translational research bridges advances in neuroscience, engineering, and computational modeling. This integration focuses on transforming research innovations into tools for potential clinical applications, addressing neurological and psychiatric conditions.
TMS-EEG: Innovating Neuroscience and Shaping Future Treatments
Transcranial Magnetic Stimulation (TMS) combined with Electroencephalography (EEG) has emerged as a transformative approach in neuroscience, extensively utilized across various research areas and clinical settings to enhance our understanding of brain functions and to develop treatments for neurological and psychiatric conditions.
About Us
Founded in 1991, Jali Medical has been a partner with researchers and clinicians throughout the history of non-invasive brain stimulation. Our extensive knowledge comes from our years of experience and collaborations with our partners and clients.
Jali Medical specializes in distributing cutting-edge neurotechnologies, including Transcranial Magnetic Stimulation (TMS), Transcranial Direct Current/Electric Stimulation (tDCS/tES), Electroencephalography (EEG), Electromyography (EMG), neuronavigation systems, and cognitive, behavioral, and movement assessment research devices. For clinical use, we offer the FDA-cleared TMS Therapy Package System and the Visor2 neuronavigation system.
We are dedicated to providing our end-users with the highest quality neuroscience equipment and accessories. Our devices have been featured in hundreds of seminal research studies and are the preferred choice for prominent research and clinical institutions.
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At Jali Medical, we believe in the power of collaboration and open dialogue. Whether you have questions, feedback, or are seeking innovative solutions, our team is eager to hear from you. Reach out today and let's start a conversation that matters.