The NEURO PRAX® TMS/tES* is a full-band DC-EEG system, which is primarily intended for use in neuroscientific applications. The system measures physiological signals such as EEG, EMG and EP in the frequency range of 0 to 1,200 Hz simultaneously and synchronously for all channels. The unique amplifier technology captures EEG activities from infraslow (0 – 0.3 Hz) to ultrafast (80 – 1,200 Hz) frequencies.
The high amplifier dynamics and the high sampling rate make the NEURO PRAX® TMS/tES* system particularly suitable for EEG measurement during transcranial magnetic stimulation and transcranial electrical stimulation with direct current (tDCS), alternating current (tACS) and random noise current (tRNS).
We can supply our high-performance full-band DC amplifiers with 32, 46 or 128 channels. The neuroConn software, specially tailored to the hardware, is intuitive, flexible and easy to use. There are a large number of software-based functions available, such as online the online correction on artifacts caused by eye and muscle movements, topographical analyses, spectral and amplitude mapping and online averaging.
Simultaneous recording of DC- EEG during non-invasive brain stimulation (NIBS), such as transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS, tRNS) or transcranial magnetic stimulation (TMS) is a painless method to evaluate the modulation of cortical oscillatory brain activity and cerebral plasticity. These methodologies allow neuroscientists to investigate a broad range of research topics, such as:
The neuroConn DC-STIMULATOR PLUS* and NEURO PRAX® TMS/tES* work hand in hand to provide noisefree EEG while stimulating the brain with tDCS and even with tACS. The DC-STIMULATOR PLUS delivers a galvanically isolated reference signal of the applied stimulation, whilst NEURO PRAX® eliminates the stimulation-induced artefacts from all EEG channels in real time using an innovative correction software. The high dynamic range of 219 mV allows to record brain signals during tES without the EEG-amplifier going into saturation.
A worldwide unique solution for neuroscientists: The DC-STIMULATOR PLUS combined with the NEURO PRAX® TMS/tES* provide artifact-free EEG-tACS.
Why combine EEG with tES (tDCS, tACS, tRNS)?
NEURO PRAX® TMS/tES*: short recovery times of 3 - 5 ms after the TMS pulse allow correction of TMS-induced artefacts in realtime for all channels
Why combine EEG with TMS?
The combination of NEURO PRAX® TMS/tES* and the DC-STIMULATOR PLUS* with the option Signal Out now allows to measure a noise-free EEG during the stimulation with alternating or random noise current.
NEURO PRAX® TMS/tES* uses an integrated innovative correction software to eliminate the stimulation-induced noise from the EEG signals. Click on the picture for more detailed information.
neuroConn product portfolio for NIBS-EEG
Closed-loop application and artefact correction for tACS-EEG
Closed-loop apparatus for brain state-dependent tES: a proof of principle based on SMR
Overview of hardware artefacts during simultaneous tES and EEG
A Method for Online Correction of Artifacts in EEG signals during Transcranial Electrical Stimulation
The first screen of the report shows the visit notes that were entered prior to the test. The second screen shows the patient identifier, the date of the test and a summary of the test results, which are described further below.
The third screen of the report shows a plot of the patient’s Eyes-Open and Eyes-Closed phybrata power aligned to their age, against the backdrop of a graph of the average power of healthy individuals across a range of ages. This chart allows the patient and their caregiver to see how the results from the current test relate to the average of healthy people the same age.
Three phybrata measures are derived from the raw sensor data:
The Phybrata Power and L/R Asymmetry are present for both the Eyes-Open and Eyes-Closed tests. Each measure is compared to a normative threshold (0.5 for Eyes-Open, 0.6 for Eyes-Closed), above which the patient’s result is flagged for further assessment. For quick identification, results below the threshold appear in green and results above the threshold appear in red.
The Phybrata Power represents the aggregate power (in Watts) of the movement of the body measured at the head. A higher than threshold Phybrata Power indicates a potential neurological impairment that should be investigated further.
The Left/Right Ratio measures any asymmetry present in the patient’s phybrata measurement. An asymmetry of zero indicates that the patient is centered. An asymmetry less than or above zero indicates that the patient leans preferentially to either the left or right side, respectively. Favoring one side beyond the normative threshold (+/- 0.5) indicates a potential orthopedic impairment that should be investigated further.
The Eyes-Closed/Eyes-Open Ratio quantifies vestibular performance. An EC/EO Ratio above the normative threshold (2.0) means the Phybrata Power is much higher with the eyes closed, indicating a potential vestibular impairment that should be investigated further.
Sample of good phybrata data
Sample of bad phybrata data
Items marked with* are investigational devices and for research use only. CAUTION - Investigational Device. Limited by Federal (or United States) law to investigational use.
