PROTXX phybrata* measurements can potentially allow clinical neurology, orthopedics, and sports medicine providers and allied physical therapy, occupational therapy, and athletic training providers to more effectively monitor and quantify the onset and progression of injury, medical-treatment, and age-related sensory, neurological, musculoskeletal, cardiovascular, and central nervous system performance impairments by:
The PROTXX machine learning engine leverages unique features in phybrata signals to identify, quantify, and monitor the treatment of complex neurophysiological impairments throughout the body.
The Phybrata sensor* attaches with a disposable adhesive for ease of use in any clinical or remote setting.
The Clinic mobile app lets users configure tests and collect data in less than a minute. Results are presented instantly via simple and intuitive reports.
The Clinic PaaS system provides data to monitor progress over time and adjust treatments more frequently for better health outcomes.
Phybrata sensing*, pioneered by PROTXX, delivers an easy-to-use wearable solution to identify and quantify changes to balance and postural stability, and to monitor each patient’s unique response to treatment and rehabilitation.
The PROTXX physiological vibration acceleration (phybrata) sensor* ³ is an unobtrusive, non-invasive, wearable device that attaches behind the user’s ear using a disposable medical adhesive. Phybrata testing requires the patient to simply stand still for 20 seconds with their eyes open and again for 20 seconds with their eyes closed. During testing, the phybrata sensor* detects microscopic involuntary motions of the body, both normal motions characteristic of healthy individuals and pathological motions caused by physiological impairments that impact balance and postural stability.
Unique spatial-domain, time-domain, and frequency-domain features detected in the phybrata signals are used to derive digital biomarkers that identify and quantify the contributions made by different physiological systems in the body to the biomechanical stabilization of the head and eyes as the reference platform used by the body to enable balance and movement. This phenomenon allows impairments to major physiological systems in the body to be classified, quantified, and monitored using their unique vibrational signatures.¹⁻⁵
Phybrata sensing* delivers a powerful new solution that enables much easier to use precision neurophysiological assessments to be carried out in any doctor’s office or via remote patient care.
Conditions such as concussions, stroke, multiple sclerosis, and Parkinson’s disease lead to disruptions that are widespread throughout the brain. Each patient can suffer from a unique combination of impairments to multiple physiological systems throughout the body, and symptoms can fluctuate significantly over time, making diagnoses difficult and treatments challenging.
Current solutions for diagnosing these multiple impairments, and monitoring the effectiveness of treatments and rehabilitation, either:
(i) require multiple time-consuming tests carried out by multiple clinical specialists using expensive lab equipment; or
(ii) they’re limited to subjective observations and reliance on patient self-reporting.
PROTXX Clinic* is used by clinical neurology, rehabilitation medicine, and sports medicine specialists and researchers to monitor and quantify changes in balance and postural stability that can reflect overall physical health, as well as the onset and progression of impairments to the central nervous system (CNS), peripheral nervous system (PNS), sensory systems (visual, vestibular, somatosensory), and musculoskeletal system. These changes can have many different causes, including participation in sports, lifestyle changes, fatigue, injuries, disease, age-related disorders, prescription medications, rehabilitation therapies, and surgical procedures. PROTXX Clinic* enables easy to use, quantitative, and more frequent monitoring of changes to balance and postural stability by benchmarking user performance vs. relevant individual and group performance metrics and target ranges and tracking individual variations over time.
|Idle Current Consumption||10||25||µA|
|Charging Cycle Life||>500||cycles|
|Data Sample Frequency||0.78||1600||Hertz|
|Low Data Rate Current||5||µA|
|Mid Data Rate Current||24||µA|
|High Data Rate Current||180||µA|
|Data Sample Frequency||25||3200||Hertz|
|Active Current (all data rates)||850||900||µA|
|Standby Current||Included in Accelerometer Standby Current|
Hope A, Vashisth U, Parker M, Ralston AB, Roper JM, Ralston JD. Phybrata Sensors and Machine Learning for Enhanced Neurophysiological Diagnosis and Treatment. Sensors 2021: 21: 7417.
Abdollah V, Dief TN, Ralston JD, Ho C, Rouhani H. Investigating the Validity of A Single Tri-axial Accelerometer Mounted on the head for Monitoring the Activities of Daily Living and the Timed-Up and Go Test. Gait & Posture. 2021; 90: 137–140.
Ralston JD, Raina A, Benson BW, Peters RM, Roper JM, Ralston AB. Physiological Vibration Acceleration (Phybrata) Sensor Assessment of Multi-System Physiological Impairments and Sensory Reweighting Following Concussion. Medical Devices: Evidence & Research. 2020; 13: 411–438.
Grafton ST, Ralston AB, Ralston JD. Monitoring of postural sway with a head-mounted wearable device: Effects of gender, participant state, and concussion. Medical Devices: Evidence & Research. 2019; 12: 151-164.
Hauenstein A, Roper JM, Ralston AB, Ralston JD. Signal classification of wearable inertial motion sensor data using a convolutional neural network. Proc IEEE-EMBS 2019 Intnl Conf Biomed & Health Informatics, May 19-22, Chicago, IL
Items marked with* are investigational devices and for research use only. CAUTION - Investigational Device. Limited by Federal (or United States) law to investigational use.
PROTXX Clinic is not an FDA-cleared device.